AutomedicationFrancoV1, Main, Exploration, bibRecord, 000801

Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.

Identifieur interne : 000801 ( Main/Exploration ); précédent : 000800; suivant : 000802

Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.

Auteurs : Brendon Stubbs [Royaume-Uni] ; Davy Vancampfort [Belgique] ; Joseph Firth [Royaume-Uni] ; Felipe B. Schuch [Brésil] ; Mats Hallgren [Suède] ; Lee Smith [Royaume-Uni] ; Benjamin Gardner [Royaume-Uni] ; Kai G. Kahl [Allemagne] ; Nicola Veronese [Italie] ; Marco Solmi [Italie] ; André F. Carvalho [Brésil] ; Ai Koyanagi [Espagne]

Source :

Journal of affective disorders [ 1573-2517 ] ; 2018.

RBID : pubmed:29329054

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Exercice physique (psychologie), Femelle (MeSH), Humains (MeSH), Indice de masse corporelle (MeSH), Jeune adulte (MeSH), Mode de vie sédentaire (MeSH), Modèles logistiques (MeSH), Mâle (MeSH), Pays en voie de développement (statistiques et données numériques), Prévalence (MeSH), Sujet âgé (MeSH), Trouble dépressif (psychologie), Trouble dépressif (épidémiologie), Études transversales (MeSH).
MESH :
- psychologie : Exercice physique, Trouble dépressif.
- statistiques et données numériques : Pays en voie de développement.
- épidémiologie : Trouble dépressif.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Indice de masse corporelle, Jeune adulte, Mode de vie sédentaire, Modèles logistiques, Mâle, Prévalence, Sujet âgé, Études transversales.

English descriptors

KwdEn :
- Adult (MeSH), Aged (MeSH), Body Mass Index (MeSH), Cross-Sectional Studies (MeSH), Depressive Disorder (epidemiology), Depressive Disorder (psychology), Developing Countries (statistics & numerical data), Exercise (psychology), Female (MeSH), Humans (MeSH), Logistic Models (MeSH), Male (MeSH), Middle Aged (MeSH), Prevalence (MeSH), Sedentary Behavior (MeSH), Young Adult (MeSH).
MESH :
- epidemiology : Depressive Disorder.
- psychology : Depressive Disorder, Exercise.
- statistics & numerical data : Developing Countries.
- Adult, Aged, Body Mass Index, Cross-Sectional Studies, Female, Humans, Logistic Models, Male, Middle Aged, Prevalence, Sedentary Behavior, Young Adult.

Abstract

BACKGROUND

Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low- and middle-income countries. This study investigated the association between SB and depression, and factors which influence this.

METHODS

Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview. The association between depression and SB (self-report) was estimated by multivariable linear and logistic regression analyses. Mediation analysis was used to identify influential factors.

RESULTS

A total of 42,469 individuals (50.1% female, mean 43.8 years) were included. People with depression spent 25.6 (95%CI8.5-42.7) more daily minutes in SB than non-depressed participants. This discrepancy was most notable in adults aged ≥ 65y (35.6min more in those with depression). Overall, adjusting for socio-demographics and country, depression was associated with a 1.94 (95%CI1.31-2.85) times higher odds for high SB (i.e., ≥ 8h/day). The largest proportion of the SB-depression relationship was explained by mobility limitations (49.9%), followed by impairments in sleep/energy (43.4%), pain/discomfort (31.1%), anxiety (30.0%), disability (25.6%), cognition (16.1%), and problems with vision (11.0%). Other health behaviors (physical activity, alcohol consumption, smoking), body mass index, and social cohesion did not influence the SB-depression relationship.

CONCLUSION

People with depression are at increased risk of engaging in high levels of SB. This first multi-national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.

DOI: 10.1016/j.jad.2017.12.104
PubMed: 29329054

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en">Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.</title>
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<affiliation wicri:level="1"><nlm:affiliation>Physiotherapy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ, United Kingdom; Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London Box SE5 8AF, United Kingdom; Faculty of Health, Social Care and Education, Anglia Ruskin University, Chelmsford, United Kingdom. Electronic address: brendon.stubbs@kcl.ac.uk.</nlm:affiliation>
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<affiliation wicri:level="1"><nlm:affiliation>KU Leuven Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven, University Psychiatric Center KU Leuven, Leuven-Kortenberg, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
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<author><name sortKey="Firth, Joseph" sort="Firth, Joseph" uniqKey="Firth J" first="Joseph" last="Firth">Joseph Firth</name>
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<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>NICM, School of Health and Science, University of Western Sydney, Australia; Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester</wicri:regionArea>
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<region type="nation">Angleterre</region>
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<author><name sortKey="Schuch, Felipe B" sort="Schuch, Felipe B" uniqKey="Schuch F" first="Felipe B" last="Schuch">Felipe B. Schuch</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Unilasalle, Canoas, Brazil; Escola de Educação Física, Fisioterapia e Dança, Porto Alegre, Brazil; Department of Psychiatry, Universidade Federal do Rio Grande do Sul / Hospital de Clínicas de Porto Alegre, Porto Alegre</wicri:regionArea>
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<author><name sortKey="Hallgren, Mats" sort="Hallgren, Mats" uniqKey="Hallgren M" first="Mats" last="Hallgren">Mats Hallgren</name>
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<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health Sciences, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
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<author><name sortKey="Smith, Lee" sort="Smith, Lee" uniqKey="Smith L" first="Lee" last="Smith">Lee Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>The Cambridge Centre for Sport and Exercise Sciences, Department of Life Sciences, Anglia Ruskin University, Cambridge, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The Cambridge Centre for Sport and Exercise Sciences, Department of Life Sciences, Anglia Ruskin University, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
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<author><name sortKey="Gardner, Benjamin" sort="Gardner, Benjamin" uniqKey="Gardner B" first="Benjamin" last="Gardner">Benjamin Gardner</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Addison House, Guy's Campus, London SE1 1UL, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Addison House, Guy's Campus, London SE1 1UL</wicri:regionArea>
<wicri:noRegion>London SE1 1UL</wicri:noRegion>
</affiliation>
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<author><name sortKey="Kahl, Kai G" sort="Kahl, Kai G" uniqKey="Kahl K" first="Kai G" last="Kahl">Kai G. Kahl</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
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<author><name sortKey="Veronese, Nicola" sort="Veronese, Nicola" uniqKey="Veronese N" first="Nicola" last="Veronese">Nicola Veronese</name>
<affiliation wicri:level="1"><nlm:affiliation>National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>National Research Council, Neuroscience Institute, Aging Branch, Padova</wicri:regionArea>
<wicri:noRegion>Padova</wicri:noRegion>
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<author><name sortKey="Solmi, Marco" sort="Solmi, Marco" uniqKey="Solmi M" first="Marco" last="Solmi">Marco Solmi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurosciences, University of Padova, Padova, Italy; Local Health Unit 17 ULSS 17, Mental Health Department, Padova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Neurosciences, University of Padova, Padova, Italy; Local Health Unit 17 ULSS 17, Mental Health Department, Padova</wicri:regionArea>
<wicri:noRegion>Padova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carvalho, Andre F" sort="Carvalho, Andre F" uniqKey="Carvalho A" first="André F" last="Carvalho">André F. Carvalho</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Clinical Medicine and Translational Psychiatry Research Group, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE</wicri:regionArea>
<placeName><region type="state">Ceará</region>
</placeName>
<orgName type="university">Université fédérale du Ceará</orgName>
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<author><name sortKey="Koyanagi, Ai" sort="Koyanagi, Ai" uniqKey="Koyanagi A" first="Ai" last="Koyanagi">Ai Koyanagi</name>
<affiliation wicri:level="4"><nlm:affiliation>Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona 08830, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos 3-5 Pabellón 11, Madrid 28029, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona 08830, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos 3-5 Pabellón 11, Madrid 28029</wicri:regionArea>
<placeName><region nuts="2" type="communauté">Communauté de Madrid</region>
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</placeName>
<orgName type="university">Université de Barcelone</orgName>
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<series><title level="j">Journal of affective disorders</title>
<idno type="eISSN">1573-2517</idno>
<imprint><date when="2018" type="published">2018</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Body Mass Index (MeSH)</term>
<term>Cross-Sectional Studies (MeSH)</term>
<term>Depressive Disorder (epidemiology)</term>
<term>Depressive Disorder (psychology)</term>
<term>Developing Countries (statistics & numerical data)</term>
<term>Exercise (psychology)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Logistic Models (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Prevalence (MeSH)</term>
<term>Sedentary Behavior (MeSH)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Exercice physique (psychologie)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Indice de masse corporelle (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mode de vie sédentaire (MeSH)</term>
<term>Modèles logistiques (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Pays en voie de développement (statistiques et données numériques)</term>
<term>Prévalence (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Trouble dépressif (psychologie)</term>
<term>Trouble dépressif (épidémiologie)</term>
<term>Études transversales (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Depressive Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Exercice physique</term>
<term>Trouble dépressif</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Depressive Disorder</term>
<term>Exercise</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Developing Countries</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Pays en voie de développement</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Trouble dépressif</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Body Mass Index</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Sedentary Behavior</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Jeune adulte</term>
<term>Mode de vie sédentaire</term>
<term>Modèles logistiques</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Sujet âgé</term>
<term>Études transversales</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low- and middle-income countries. This study investigated the association between SB and depression, and factors which influence this.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview. The association between depression and SB (self-report) was estimated by multivariable linear and logistic regression analyses. Mediation analysis was used to identify influential factors.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A total of 42,469 individuals (50.1% female, mean 43.8 years) were included. People with depression spent 25.6 (95%CI8.5-42.7) more daily minutes in SB than non-depressed participants. This discrepancy was most notable in adults aged ≥ 65y (35.6min more in those with depression). Overall, adjusting for socio-demographics and country, depression was associated with a 1.94 (95%CI1.31-2.85) times higher odds for high SB (i.e., ≥ 8h/day). The largest proportion of the SB-depression relationship was explained by mobility limitations (49.9%), followed by impairments in sleep/energy (43.4%), pain/discomfort (31.1%), anxiety (30.0%), disability (25.6%), cognition (16.1%), and problems with vision (11.0%). Other health behaviors (physical activity, alcohol consumption, smoking), body mass index, and social cohesion did not influence the SB-depression relationship.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>People with depression are at increased risk of engaging in high levels of SB. This first multi-national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">29329054</PMID>
<DateCompleted><Year>2018</Year>
<Month>09</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2021</Year>
<Month>01</Month>
<Day>09</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1573-2517</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>229</Volume>
<PubDate><Year>2018</Year>
<Month>03</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Journal of affective disorders</Title>
<ISOAbbreviation>J Affect Disord</ISOAbbreviation>
</Journal>
<ArticleTitle>Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.</ArticleTitle>
<Pagination><MedlinePgn>231-238</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jad.2017.12.104</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low- and middle-income countries. This study investigated the association between SB and depression, and factors which influence this.</AbstractText>
<AbstractText Label="METHODS">Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview. The association between depression and SB (self-report) was estimated by multivariable linear and logistic regression analyses. Mediation analysis was used to identify influential factors.</AbstractText>
<AbstractText Label="RESULTS">A total of 42,469 individuals (50.1% female, mean 43.8 years) were included. People with depression spent 25.6 (95%CI8.5-42.7) more daily minutes in SB than non-depressed participants. This discrepancy was most notable in adults aged ≥ 65y (35.6min more in those with depression). Overall, adjusting for socio-demographics and country, depression was associated with a 1.94 (95%CI1.31-2.85) times higher odds for high SB (i.e., ≥ 8h/day). The largest proportion of the SB-depression relationship was explained by mobility limitations (49.9%), followed by impairments in sleep/energy (43.4%), pain/discomfort (31.1%), anxiety (30.0%), disability (25.6%), cognition (16.1%), and problems with vision (11.0%). Other health behaviors (physical activity, alcohol consumption, smoking), body mass index, and social cohesion did not influence the SB-depression relationship.</AbstractText>
<AbstractText Label="CONCLUSION">People with depression are at increased risk of engaging in high levels of SB. This first multi-national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.</AbstractText>
<CopyrightInformation>Copyright © 2018 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Stubbs</LastName>
<ForeName>Brendon</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Physiotherapy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ, United Kingdom; Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London Box SE5 8AF, United Kingdom; Faculty of Health, Social Care and Education, Anglia Ruskin University, Chelmsford, United Kingdom. Electronic address: brendon.stubbs@kcl.ac.uk.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vancampfort</LastName>
<ForeName>Davy</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>KU Leuven Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven, University Psychiatric Center KU Leuven, Leuven-Kortenberg, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Firth</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>NICM, School of Health and Science, University of Western Sydney, Australia; Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schuch</LastName>
<ForeName>Felipe B</ForeName>
<Initials>FB</Initials>
<AffiliationInfo><Affiliation>Unilasalle, Canoas, Brazil; Escola de Educação Física, Fisioterapia e Dança, Porto Alegre, Brazil; Department of Psychiatry, Universidade Federal do Rio Grande do Sul / Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hallgren</LastName>
<ForeName>Mats</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Lee</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>The Cambridge Centre for Sport and Exercise Sciences, Department of Life Sciences, Anglia Ruskin University, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gardner</LastName>
<ForeName>Benjamin</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Addison House, Guy's Campus, London SE1 1UL, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kahl</LastName>
<ForeName>Kai G</ForeName>
<Initials>KG</Initials>
<AffiliationInfo><Affiliation>Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Veronese</LastName>
<ForeName>Nicola</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Solmi</LastName>
<ForeName>Marco</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Neurosciences, University of Padova, Padova, Italy; Local Health Unit 17 ULSS 17, Mental Health Department, Padova, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carvalho</LastName>
<ForeName>André F</ForeName>
<Initials>AF</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Medicine and Translational Psychiatry Research Group, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Koyanagi</LastName>
<ForeName>Ai</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona 08830, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos 3-5 Pabellón 11, Madrid 28029, Spain.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>ICA-CL-2017-03-001</GrantID>
<Acronym>DH_</Acronym>
<Agency>Department of Health</Agency>
<Country>United Kingdom</Country>
</Grant>
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<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>01</Month>
<Day>03</Day>
</ArticleDate>
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<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>J Affect Disord</MedlineTA>
<NlmUniqueID>7906073</NlmUniqueID>
<ISSNLinking>0165-0327</ISSNLinking>
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<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D015992" MajorTopicYN="N">Body Mass Index</DescriptorName>
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<MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Depression</Keyword>
<Keyword MajorTopicYN="Y">Low- and middle-income countries</Keyword>
<Keyword MajorTopicYN="Y">Physical activity</Keyword>
<Keyword MajorTopicYN="Y">Sedentary behavior</Keyword>
<Keyword MajorTopicYN="Y">Sitting</Keyword>
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Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.

Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries.

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